PUBLISHED WORK
FOXO nuclear shuttling dynamics are stimulus-dependent and correspond with cell fate (2023)
Lasick, K. A., Jose, E., Samayoa, A. M., Shanks, L., Pond, K. W., Thorne, C. A., & Paek, A. L.
Molecular Biology of the Cell, 34(3), ar21.https://doi.org/10.1091/mbc.E22-05-0193
Feedback in the β-catenin destruction complex imparts bistability and cellular memory. (2023)
Cantoria, M.J., Alizadeh, E., Ravi, J., Varghese, R.P., Bunnag, N., Pond, K.W., Kettenbach, A.N., Ahmed, Y., Paek, A.L., Tyson, J.J., Doubrovinski, K., and Thorne C.A.
Proceedings of the National Academy of Sciences, 120(2). https://doi.org/10.1073/pnas.2208787120
Live-cell imaging in human colonic monolayers reveals ERK waves limit the stem cell compartment to maintain epithelial homeostasis (2022)
Pond K.W., Morris J.M.,Alkhimenok O., Varghese R.P., Cabel C.R., Ellis N.A., Chakrabarti J., Zavros Y., Merchant J.L., Thorne C.A.†, Paek A.L.†
Elife e78837. †Corresponding Authors https://doi.org/10.7554/eLife.78837
Weakly supervised deep learning for detecting and counting dead cells in microscopy images (2019)
Chen S., Li A.,Lasick K., Huynh J., Powers L., Roveda J., & Paek A.
2019 18th IEEE International Conference On Machine Learning And Applications (ICMLA). IEEE, 2019. 10.1109/ICMLA.2019.00282
Designing combination therapies with modeling chaperoned machine learning (2019)
Zhang, Y., Huynh, J., Liu, G., Ballweg, R., Aryeh, K., Paek, A., Zhang, T.
PLOS Computational Biology. 10.1371
Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages (2018)
Chakrabarti, S.*, Paek, A. L.*, Reyes, J., Lasick, K. A., Lahav, G., & Michor, F.
Nature communications, 9(1), 5372.
* These authors contributed equally
Drug-induced aneuploidy and polyploidy is a mechanism of disease relapse in MYC/BCL2-addicted diffuse large B-cell lymphoma (2018)
Islam, S., Paek, A. L., Hammer, M., Rangarajan, S., Ruijtenbeek, R., Cooke, L., … & Mahadevan, D.
Oncotarget.
A dynamical framework for complex fractional killing (2017)
Ballweg, R., Paek A.L. and Tongli Zhang
Scientific Reports
Cell-to-cell variation in p53 dynamics leads to fractional killing (2016)
Paek A.L., Liu J.C., Loewer A., Forrester W.C. and Lahav G.
Cell 165: 631-642.
Draft Genome Sequence of the Ale-Fermenting Saccharomyces cerevisiae Strain GSY2239 (2015)
U’Ren, J. M., Wisecaver, J. H., Paek, A. L., Dunn, B. L., & Hurwitz, B. L.
Genome announcements, 3(4).
DNA replication: failures and inverted fusions (2011)
Carr A.M., Paek A.L., Weinert T.
Seminars in Cell & Developmental Biology 22:866-874.
Choreography of the 9-1-1 checkpoint complex: DDK puts a check on the checkpoints (2010)
Paek A.L. and Weinert T
Molecular Cell. 40:505-506.
The role of replication bypass pathways in dicentric chromosome formation in budding yeast (2010)
Paek A.L., Jones H., Kaochar S., Weinert T.
Genetics. 186:1161-1173.
Fusion of nearby inverted repeats by a replication-based mechanism leads to formation of dicentric and acentric chromosomes that cause genome instability in budding yeast (2009)
Paek A.L.*, Kaochar S.*, Jones H., Elezaby A., Shanks L., Weinert T.
Genes and Development. 23: 2861-2875.
* These authors contributed equally
The replication fork’s five degrees of freedom, their failure and genome rearrangements (2009)
Weinert T., Kaochar S., Jones H., Paek A., Clark A.J.
Current Opinion in Cell Biology. 21: 778-784.
Evolution of variants of yeast site-specific recombinase Flp that utilize native genomic sequences as recombination target sites (2006)
Bolusani S., Ma C.H., Paek A., Konieczka J.H., Jayaram M., Voziyanov Y.
Nucleic Acids Research. 34:5259-5269.
Mechanisms for Chromosome and Plasmid Segregation (2006)
Ghosh S.K., Hajra S., Paek A., Jayaram M.PLOS Computational Biology. 10.1371
Annual Review of Biochemistry. 75: 211-241.
Recombination of hybrid target sites by binary combinations of Flp variants: mutations that foster interprotomer collaboration and enlarge substrate tolerance (2004)
Konieczka J.H., Paek A., Jayaram M., Voziyanov Y.
Journal of Molecular Biology. 339: 365-378.